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Nearly one in five adults with obesity has used a glucagon-like peptide-1 (GLP-1), highlighting the scale of this challenge

Due to their weekly dosing schedule and greater mean weight loss seen in trials (15% for semaglutide and 21% for tirzepatide, compared to 8% with liraglutide), semaglutide and tirzepatide are more frequently prescribed than liraglutide for treatment of obesity [33,34,35]

GLP-1 therapy addresses hyperglycaemia whilst potentially contributing to blood pressure reduction, simplifying the therapeutic regimen

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